Pharmacology – University of Copenhagen

Pharmacology

MIND Pharmacology offers a broad education in all pharmacological disciplines used for drug candidate selection. Through lectures and workshops within in vitro pharmacology, in vivo disease animal models, pharmacokinetics and ADMET, the course offers participants to work with real challenges of ‘drug candidate pharmacological behavior’ in the drug development process.

The broad nature of the course enables participants to understand a large variety of central goals and challenges in drug discovery and development and to optimize work across specialist areas in his or her own organization. The course offers high level pharmacological science as well as hands-on experience with pharmacokinetic and pharmacodynamic study design, data analysis and data interpretation.

WHAT YOU WILL LEARN 

During the course you will:

  • Obtain basic and integrated understanding of pharmacology methodology in drug discovery and development disciplines
  • Understand and conduct state-of the art calculations and data interpretations within pharmacokinetics and especially within pharmacodynamics
  • Get broad understanding of all aspects of ADMET based drug candidate selections
  • Understand basic validation of animal models for in vivo pharmacological drug candidate selection
  • Understand and validate methods applied for in vitro pharmacological drug candidate selection
  • Obtain a large overview of current state-of-the art pharmacology models
  • Get professional communication skills within pharmacological terminology

"The course is of the highest quality, especially the last two days have been intense with competent lecturers who have extensive knowledge of their area while they at the same time are able to convey their knowledge in an exciting and relevant way." - Casper Tind Hansen, CEO, Pcovery.

COURSE CONTENT

The course will teach the basic concepts of general pharmacology. Emphasis is on pharmacokinetics with hands-on calculations. There is focus on experimental in vitro and in vivo tools and on animal experimental models for various diseases including modern experimental techniques.

The course covers the following areas:

  • General pharmacology (pharmacodynamics)
  • Pharmacokinetics (basic concepts, extra vascular dosing using a one-compartment model, IV administration using 1- and 2 compartment models, elimination: metabolism and excretion, hands-on calculation in an Excel spreadsheet)
  • Exploratory pharmacology (measurement of pharmacological effect, safety pharmacology)
  • In vitro pharmacology, concepts and methodology (ADME; biomarkers; metabolism; transporters)
  • In vivo pharmacology, methodology (animal models for cardiovascular diseases, obesity, bone and joint diseases and pain; behavioural animal models.)

"What I like about this course is that it is not only theory, mathematical formulas and dose response curves, but there is also focus on how we can use this in our daily work." - Madaleine Dahlbäck, Senior Scientist, Novo Nordisk

MIND Pharmacology contains lectures and discussions throughout all aspects of applied pharmacology in drug discovery and developments processes. Experienced specialists from Leo Pharma, Novo Nordisk, Lundbeck and Copenhagen University presents basic and applied pharmacology illustrated with state-of-the art examples. Whereas topics include in vitro and in vivo pharmacological drug candidate selection and ADMET drug candidate selection criteria, a special focus will be given to pharmacokinetic modeling, calculation and data interpretation. You will have good opportunities to network during discussion, workshops, and breaks.

PARTICIPANTS

Participants must meet the following criteria: 
• A relevant bachelor degree or equivalent 
• A minimum of 2 years of relevant job experience 
• Be proficient in English

COURSE DETAILS

Course dates

5 days, 7-10 May + 13 May 2019

Course fee

  • DKK 10,750 for EU/EEA citizens  
  • DKK 12,488 for non-EU/EEA citizens

Application deadline

Closed

EXAMINATION

2 hours written examination under invigilation.
Problems based on a case description, supplemented with multiple choice and short essay questions. Written aids allowed.

Credit 

2,5 ECTS

Examination date

Written exam 16 May 2019 from 9:00 to 11:00

Ekstra information / Sidebar

Leading lecturers and experts

Leading university researchers

Anne-Marie Heegaard, University of Copenhagen
Bente Steffansen, University of Copenhagen
Darryl Pickering, University of Copenhagen
Helle Waagepetersen, University of Copenhagen
Majid Sheykhzade, University of Copenhagen
Ole J. Bjerrum, University of Copenhagen
Uffe Kristiansen, University of Copenhagen

Visiting experts from the pharmaceutical industry

Bjarke Ebert, H. Lundbeck
Frank Larsen, H. Lundbeck
Inge de Jong, H. Lundbeck
Jørgen Olsen, Novo Nordisk
Kim Kristensen, Novo Nordisk
Kim Sonne, LEO Pharma
Lasse Tengbjerg Hansen, Novo Nordisk
Mette Guldbrandt, Novo Nordisk
Peter B. Johansen, Novo Nordisk